Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235830 | 1.00 | HPGD (0.53) | HPGDMEN1KMT2AALDH1A1HDAC3 | |
| SCHEMBL11237791 | 1.00 | HPGD (0.53) | HPGDMEN1KMT2AALDH1A1HDAC3 | |
| SCHEMBL11236735 | 1.00 | HPGD (0.53) | HPGDMEN1KMT2AALDH1A1HDAC3 | |
| SCHEMBL11246827 | 0.88 | HPGD (0.46) | HPGDMEN1KMT2AALDH1A1S1PR1 | |
| SCHEMBL11245458 | 0.88 | ALDH1A1 (0.57) | HPGDMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11238170 | 0.87 | FAAH (0.55) | HPGDMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11236131 | 0.86 | CYP4F2 (0.56) | HPGDALDH1A1S1PR1 | |
| SCHEMBL11244302 | 0.86 | CYP4F2 (0.56) | HPGDALDH1A1S1PR1 | |
| SCHEMBL11240733 | 0.86 | CYP4F2 (0.56) | HPGDALDH1A1S1PR1 | |
| SCHEMBL11243340 | 0.86 | CYP4F2 (0.56) | HPGDALDH1A1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |