Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | HPGD | P15428 | 9/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | CASP1 | P29466 | 4/20 | 0.45 |
| ▸ | CASP7 | P55210 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10977751 | 0.99 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL10976629 | 0.91 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL10972608 | 0.90 | HSD17B10 (0.45) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10977470 | 0.89 | HSD17B10 (0.44) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL10981081 | 0.88 | CACNA1C (0.52) | KDM4EALDH1A1HPGDNPSR1GAA | |
| SCHEMBL10979981 | 0.88 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL10973525 | 0.85 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10975527 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL5075369 | 0.84 | ABCC9 (0.53) | KDM4EALDH1A1HPGDNPSR1LMNA | |
| SCHEMBL10978148 | 0.81 | KMT2A (0.53) | KDM4EALDH1A1HPGDNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321384-A | Antihypertensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |