Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | PGR | P06401 | 6/20 | 0.59 |
| ▸ | AR | P10275 | 6/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236389 | 1.00 | CYP3A4 (0.59) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL11245421 | 0.85 | CYP17A1 (0.61) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL11245428 | 0.85 | CYP17A1 (0.61) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL9622429 | 0.84 | LMNA (0.67) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL13941337 | 0.84 | LMNA (0.67) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL853001 | 0.84 | LMNA (0.67) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL10938509 | 0.83 | NR3C1 (0.67) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL11117577 | 0.83 | NR3C1 (0.67) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL11117579 | 0.83 | NR3C1 (0.67) | CYP3A4PGRARNR3C1ABCB11 | |
| SCHEMBL10605027 | 0.83 | LMNA (0.48) | CYP3A4PGRARNR3C1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |