Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | PGR | P06401 | 4/20 | 0.67 |
| ▸ | SHBG | P04278 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117577 | 1.00 | NR3C1 (0.67) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL10938509 | 1.00 | NR3C1 (0.67) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL9348215 | 0.90 | LMNA (0.62) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL9348129 | 0.90 | LMNA (0.62) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL9348134 | 0.90 | LMNA (0.62) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL10821749 | 0.88 | SHBG (0.63) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL10821748 | 0.88 | SHBG (0.63) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL11319124 | 0.88 | SHBG (0.71) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL10820974 | 0.88 | LMNA (0.60) | NR3C1CYP2C19LMNAMEN1KMT2A | |
| SCHEMBL10820973 | 0.88 | LMNA (0.60) | NR3C1CYP2C19LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440689-A | Acyloxysteroids and process for producing same | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1984-04-03 | — | — | US | disclosed |
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |