Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367710 | 0.93 | MAPT (0.42) | GFERMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11242157 | 0.91 | MEN1 (0.35) | GFERMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11248927 | 0.83 | ALDH1A1 (0.39) | GFERMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11230933 | 0.82 | MEN1 (0.35) | GFERMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11461153 | 0.79 | MEN1 (0.49) | GFERMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11236725 | 0.78 | MAPT (0.39) | GFERMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11243411 | 0.78 | TRPV1 (0.37) | MEN1KMT2ANPC1RAB9ACNR2 | |
| SCHEMBL11367233 | 0.77 | NPC1 (0.41) | MAPTNPSR1MEN1KMT2ANPC1 | |
| SCHEMBL11239287 | 0.77 | NPSR1 (0.38) | GFERMAPTNPSR1MEN1KMT2A | |
| SCHEMBL11369427 | 0.75 | NPC1 (0.40) | MAPTNPSR1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |