Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367714 | 0.93 | MAPT (0.39) | MAPTGFERNPSR1MEN1KMT2A | |
| SCHEMBL11461152 | 0.81 | MEN1 (0.43) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11367236 | 0.80 | PGR (0.39) | MAPTGFERNPSR1MEN1KMT2A | |
| SCHEMBL11236720 | 0.78 | GFER (0.42) | MAPTGFERNPSR1MEN1KMT2A | |
| SCHEMBL11380867 | 0.77 | PGR (0.37) | MAPTGFERNPSR1MEN1KMT2A | |
| SCHEMBL11367710 | 0.73 | MAPT (0.42) | MAPTGFERNPSR1MEN1KMT2A | |
| SCHEMBL11441976 | 0.71 | ALDH1A1 (0.43) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL11244555 | 0.69 | CNR2 (0.36) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL11472573 | 0.69 | MEN1 (0.45) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL11242157 | 0.67 | MEN1 (0.35) | MAPTGFERNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |