Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244138 | 0.89 | GCGR (0.61) | TDP1GCGRNPC1POLBPKM | |
| SCHEMBL11251747 | 0.89 | GCGR (0.55) | TDP1GCGRNPC1POLBPKM | |
| SCHEMBL11242062 | 0.89 | TDP1 (0.67) | TDP1GCGRNPSR1S1PR1NPC1 | |
| SCHEMBL11248869 | 0.84 | TDP1 (0.64) | TDP1GCGRNPSR1NPC1RAB9A | |
| SCHEMBL11303176 | 0.84 | GCGR (0.59) | TDP1GCGRNPSR1S1PR1GAA | |
| SCHEMBL11383033 | 0.83 | MEN1 (0.53) | TDP1GCGRGAANPC1POLB | |
| SCHEMBL11240737 | 0.83 | S1PR1 (0.59) | LRRK2TDP1GCGRNPSR1S1PR1 | |
| SCHEMBL11239199 | 0.83 | LRRK2 (0.50) | LRRK2TDP1GAANPC1RAB9A | |
| SCHEMBL11242220 | 0.83 | S1PR1 (0.61) | LRRK2TDP1GCGRNPSR1S1PR1 | |
| SCHEMBL11233013 | 0.82 | PNLIP (0.53) | TDP1GCGRNPSR1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |