SCHEMBL11237151

SCHEMBL11237151

CCCCCCCCc1ccc(N(c2ccc(CCCCCCCC)cc2)C2(c3ccc(N(CC)CC)cc3C)OC(=O)c3ncccc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
STAT3 P40763 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CNR2 P34972 3/20 0.32
TRPV1 Q8NER1 2/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
SRC P12931 2/20 0.31
IGLV6-57 P01721 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11241310 0.91 CNR2 (0.32) HTTCNR2TRPV1CA12CA1
SCHEMBL11232619 0.88 FFAR4 (0.35) LMNASTAT3HTTSMN1; SMN2CNR2
SCHEMBL11241233 0.86 HTT (0.35) LMNASTAT3HTTSMN1; SMN2IGLV6-57
SCHEMBL11372341 0.85 CA12 (0.38) LMNASMN1; SMN2CNR2CA12CA1
SCHEMBL11245434 0.83 TRPV1 (0.35) CNR2TRPV1CA12CA1CA2
SCHEMBL11239324 0.83 TRPV1 (0.35) CNR2TRPV1CA12CA1CA2
SCHEMBL11244452 0.81 TRPV1 (0.36) CNR2TRPV1CYP2C19
SCHEMBL11235691 0.79 CNR2 (0.36) LMNASTAT3HTTSMN1; SMN2CNR2
SCHEMBL11239963 0.79 CNR2 (0.36) LMNACNR2TRPV1FAAHCYP2C19
SCHEMBL11233667 0.77 RPS6KA2 (0.37) LMNASTAT3HTTSMN1; SMN2IGLV6-57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4211872-A COLOR FORMERS FREEDOM CHEMICAL COMPANY 1980-07-08 US claimed
US-4337340-A FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS STERLING DRUG INC. (US) 1982-06-29 US disclosed
US-4243250-A FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS STERLING DRUG INC. (US) 1981-01-06 US disclosed
US-4211872-A COLOR FORMERS FREEDOM CHEMICAL COMPANY 1980-07-08 US disclosed