Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237305 | 0.93 | S100B (0.34) | RPS6KA2S100BALDH1A1HSD17B10CASP1 | |
| SCHEMBL11241310 | 0.86 | CNR2 (0.32) | ALDH1A1HSD17B10CASP1CASP7MAPK1 | |
| SCHEMBL11244078 | 0.85 | MEN1 (0.36) | ALDH1A1HPGDCYP3A4MAPTMEN1 | |
| SCHEMBL8944016 | 0.83 | S100B (0.38) | RPS6KA2S100BALDH1A1HSD17B10CASP1 | |
| SCHEMBL11241233 | 0.82 | HTT (0.35) | RPS6KA2S100BALDH1A1HSD17B10CASP1 | |
| SCHEMBL11235691 | 0.81 | CNR2 (0.36) | RPS6KA2MAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL11380886 | 0.81 | RPS6KA2 (0.44) | RPS6KA2S100BALDH1A1HSD17B10CASP1 | |
| SCHEMBL11239287 | 0.80 | NPSR1 (0.38) | RPS6KA2S100BALDH1A1HSD17B10CASP1 | |
| SCHEMBL11246307 | 0.80 | NPSR1 (0.38) | RPS6KA2S100BALDH1A1HSD17B10CASP1 | |
| SCHEMBL11239595 | 0.79 | HSD17B10 (0.38) | RPS6KA2S100BALDH1A1HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |