Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249686 | 0.87 | TRPV1 (0.34) | TRPV1ALDH1A1CYP3A4HPGDCYP1A2 | |
| SCHEMBL11237226 | 0.84 | TRPV1 (0.36) | TRPV1ALDH1A1CYP3A4HPGDCYP1A2 | |
| SCHEMBL1882657 | 0.84 | KMT2A (0.42) | ALDH1A1CYP3A4HPGDCYP1A2CYP2C19 | |
| SCHEMBL11235932 | 0.83 | ALDH1A1 (0.38) | ALDH1A1CYP3A4HPGDCYP1A2CYP2C19 | |
| SCHEMBL11373082 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP3A4HPGDCYP1A2CYP2C19 | |
| SCHEMBL11237151 | 0.81 | LMNA (0.32) | TRPV1CYP2C19CNR2 | |
| SCHEMBL11239963 | 0.78 | CNR2 (0.36) | TRPV1ALDH1A1CYP3A4HPGDCYP1A2 | |
| SCHEMBL11245349 | 0.77 | GSK3A (0.36) | ALDH1A1HPGDKMT2ACNR2KAT2B | |
| SCHEMBL11228890 | 0.76 | KMT2A (0.36) | ALDH1A1HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL9462507 | 0.75 | CYP2C19 (0.41) | ALDH1A1CYP3A4HPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | claimed |
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |