Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237151 | 0.91 | LMNA (0.32) | CNR2SRCCYP2C19TRPV1CA12 | |
| SCHEMBL11232619 | 0.88 | FFAR4 (0.35) | CNR2RARBTRPV1CA12CA1 | |
| SCHEMBL11239963 | 0.88 | CNR2 (0.36) | CNR2ALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL11233667 | 0.86 | RPS6KA2 (0.37) | ALDH1A1CYP3A4HPGDMEN1CYP2C19 | |
| SCHEMBL11237305 | 0.85 | S100B (0.34) | ALDH1A1CYP3A4HPGDMEN1CYP2C19 | |
| SCHEMBL11372341 | 0.83 | CA12 (0.38) | CNR2ALDH1A1MEN1CYP2C19KMT2A | |
| SCHEMBL11245434 | 0.83 | TRPV1 (0.35) | CNR2CYP2C19RARBTRPV1CA12 | |
| SCHEMBL11239324 | 0.83 | TRPV1 (0.35) | CNR2CYP2C19RARBTRPV1CA12 | |
| SCHEMBL11249686 | 0.81 | TRPV1 (0.34) | CNR2ALDH1A1CYP3A4HPGDCYP1A2 | |
| SCHEMBL8944016 | 0.77 | S100B (0.38) | ALDH1A1CYP3A4HPGDMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |