Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148681 | 0.77 | NR1H4 (0.53) | — | |
| SCHEMBL11560468 | 0.75 | MET (0.52) | — | |
| SCHEMBL11555954 | 0.74 | LRRK2 (0.54) | — | |
| SCHEMBL6957526 | 0.71 | PRMT5 (0.51) | PRMT5DHODH | |
| SCHEMBL11563381 | 0.71 | LRRK2 (0.55) | — | |
| SCHEMBL28587775 | 0.70 | FFAR1 (0.53) | PRMT5XDHCHEK2DHODHMCL1 | |
| SCHEMBL11561500 | 0.69 | LRRK2 (0.63) | — | |
| SCHEMBL11298259 | 0.69 | BTK (0.46) | XDH | |
| SCHEMBL10553815 | 0.69 | PTGER1 (0.50) | — | |
| SCHEMBL9825949 | 0.68 | PTPN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57158779-A | — | — | None | — | — | JP | disclosed |
| JP-S57158779-A | DIHYDROPYRIMIDINE DERIVATIVE AND ITS SALT, THEIR PREPARATION AND ANTIALLERGIC CONTAINING THE SAME | FUJISAWA PHARMACEUT CO LTD | 1982-09-30 | — | — | JP | disclosed |