Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224090 | 0.77 | MAPK1 (0.44) | TDP1LMNACYP3A4MAPTTP53 | |
| SCHEMBL10442008 | 0.71 | MAPK1 (0.50) | KDM4EALDH1A1TDP1CA2TSHR | |
| SCHEMBL11223007 | 0.70 | TDP1 (0.40) | KDM4EALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL8668158 | 0.69 | ABCB11 (0.45) | KDM4EALDH1A1TDP1CYP3A4ALOX12 | |
| SCHEMBL6055563 | 0.69 | ABCB11 (0.43) | KDM4EALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL28447739 | 0.68 | ABCB11 (0.41) | KDM4EALDH1A1TDP1LMNACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL25292376 | 0.68 | ABCB11 (0.42) | KDM4EALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL8667615 | 0.68 | ALDH1A1 (0.55) | KDM4EALDH1A1TDP1CYP3A4ALOX12 | |
| SCHEMBL3006462 | 0.67 | KDM4E (0.48) | KDM4EALDH1A1TDP1LMNACYP3A4 | |
| SCHEMBL9326165 | 0.65 | KDM4E (0.47) | KDM4EALDH1A1TDP1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320144-A | Fungicidal use of diphenyl esters of alkylenes | GAF CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |