Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 10/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238856 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAOBTSHRKMT2ACYP1A2 | |
| SCHEMBL11227836 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAOBMAOA | |
| SCHEMBL11234155 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAOBLMNASMN1; SMN2RAB9A | |
| SCHEMBL11235876 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAOBLMNAKMT2AL3MBTL1 | |
| SCHEMBL11227476 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAOBHTTLMNATSHR | |
| SCHEMBL11232506 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAOBLMNATSHRSMN1; SMN2 | |
| SCHEMBL11245007 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAOBLMNASMN1; SMN2KMT2A | |
| SCHEMBL11240239 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2PTGS2RAB9A | |
| SCHEMBL11224073 | 0.76 | MAOB (0.43) | ALDH1A1MAOB | |
| SCHEMBL11232516 | 0.72 | MAOB (0.39) | ALDH1A1MAOBTSHRMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327091-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | claimed |
| EP-0003360-B1 | AZATHIANAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR UTILISATION | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | claimed |
| US-4213980-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | claimed |
| US-4327091-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4213980-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |