Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234155 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAOBKMT2AMEN1USP2 | |
| SCHEMBL11227836 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAOB | |
| SCHEMBL11238000 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MAOBKMT2ATSHRCYP2C9 | |
| SCHEMBL11235876 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAOBKMT2AMEN1USP2 | |
| SCHEMBL11227476 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAOBKMT2AMEN1TSHR | |
| SCHEMBL11232506 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAOBKMT2AMEN1TSHR | |
| SCHEMBL11245007 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAOBKMT2AMEN1POLB | |
| SCHEMBL11240239 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1USP2POLB | |
| SCHEMBL11227315 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAOBKMT2AMEN1TSHR | |
| SCHEMBL11224073 | 0.78 | MAOB (0.43) | ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327091-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | claimed |
| EP-0003360-B1 | AZATHIANAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR UTILISATION | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | claimed |
| US-4213980-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | claimed |
| US-4327091-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4213980-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |