Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234155 | 0.93 | ALDH1A1 (0.52) | ALDH1A1MAOBMEN1KMT2ALMNA | |
| SCHEMBL11238856 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAOBMEN1KMT2AUSP2 | |
| SCHEMBL11227836 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAOB | |
| SCHEMBL11240239 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL11227476 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAOBMEN1KMT2ALMNA | |
| SCHEMBL11238000 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAOBKMT2ALMNAL3MBTL1 | |
| SCHEMBL11232506 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAOBMEN1KMT2ALMNA | |
| SCHEMBL11245007 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAOBMEN1KMT2ALMNA | |
| SCHEMBL11234091 | 0.76 | LMNA (0.40) | ALDH1A1PTPN1TOP2AMAOBLMNA | |
| SCHEMBL11224073 | 0.74 | MAOB (0.43) | ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327091-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4213980-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |