Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SCD | O00767 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220429 | 0.82 | ADORA3 (0.62) | ADORA3MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11246100 | 0.79 | MAPT (0.53) | ADORA3MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6942413 | 0.77 | ADORA3 (1.00) | ADORA3MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11249270 | 0.76 | NPC1 (0.53) | ADORA3MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL77204 | 0.75 | SMN1; SMN2 (0.70) | ADORA3MAPTNPSR1KDM4EHPGD | |
| SCHEMBL13056089 | 0.75 | RAB9A (0.54) | ADORA3MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL460764 | 0.73 | RAB9A (0.62) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL18094502 | 0.73 | ADORA3 (0.71) | ADORA3MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11241140 | 0.73 | TYK2 (0.47) | ADORA3MAPTNPSR1KDM4EHPGD | |
| SCHEMBL11227159 | 0.73 | SMN1; SMN2 (0.50) | ADORA3MAPTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343945-A | 5-Benzamido-3-trichloromethyl-1,2,4-thiadiazoles and their use as herbicides, fungicides and insecticides | OLIN CORPORATION (US) | 1982-08-10 | — | — | US | disclosed |