Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239956 | 0.96 | CYP19A1 (0.47) | CYP19A1MEN1KMT2ATBXAS1LMNA | |
| SCHEMBL11243518 | 0.91 | TBXAS1 (0.47) | CYP19A1MEN1KMT2ATBXAS1MAPK1 | |
| SCHEMBL11237998 | 0.89 | TP53 (0.50) | CYP19A1TBXAS1 | |
| SCHEMBL11243839 | 0.89 | QPCT (0.49) | CYP19A1MEN1KMT2ATBXAS1MAPK1 | |
| SCHEMBL11243657 | 0.86 | MEN1 (0.54) | MEN1KMT2ALMNA | |
| SCHEMBL11243953 | 0.85 | TP53 (0.48) | CYP19A1 | |
| SCHEMBL11239378 | 0.85 | QPCT (0.50) | CYP19A1MEN1KMT2ATBXAS1MAPK1 | |
| SCHEMBL11242355 | 0.85 | HMOX1 (0.45) | CYP19A1MEN1KMT2ATBXAS1LMNA | |
| SCHEMBL11241969 | 0.82 | CYP19A1 (0.48) | CYP19A1TBXAS1 | |
| SCHEMBL11249800 | 0.82 | MEN1 (0.55) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |