Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237998 | 0.96 | TP53 (0.50) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11246686 | 0.92 | TP53 (0.47) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11239378 | 0.90 | QPCT (0.50) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11230325 | 0.89 | LMNA (0.45) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11239956 | 0.89 | CYP19A1 (0.47) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11249800 | 0.87 | MEN1 (0.55) | ALDH1A1QPCTKDM4ETSHRCYP1A2 | |
| SCHEMBL11243839 | 0.86 | QPCT (0.49) | TP53ALDH1A1QPCTTSHRCYP19A1 | |
| SCHEMBL11238178 | 0.85 | CYP19A1 (0.46) | CYP19A1 | |
| SCHEMBL11235683 | 0.85 | HMOX1 (0.55) | TP53ALDH1A1QPCTHMOX1 | |
| SCHEMBL11245777 | 0.84 | QPCT (0.49) | TP53ALDH1A1QPCTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |