Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065109 | 0.82 | LTA4H (0.49) | LIPEMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL9706430 | 0.82 | LTA4H (0.45) | LIPEMEN1ALDH1A1KMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL6243653 | 0.79 | ALDH1A1 (0.47) | LIPEMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL2091733 | 0.78 | LTA4H (0.37) | LTA4H | |
| SCHEMBL2091737 | 0.78 | MEN1 (0.45) | LIPEMEN1KMT2ALTA4HHRH3 | |
| SCHEMBL61425 | 0.69 | NOTUM (0.58) | MEN1ALDH1A1MAPTKMT2AHRH3 | |
| SCHEMBL18798926 | 0.68 | TEAD1 (0.56) | LIPEMMP2 | |
| SCHEMBL9052835 | 0.68 | NOTUM (0.56) | LMNATRPV1 | |
| SCHEMBL1035980 | 0.66 | ALDH1A1 (0.65) | MEN1ALDH1A1KMT2A | |
| SCHEMBL5536446 | 0.65 | GAA (0.71) | MEN1KMT2AHSD11B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |