Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065109 | 0.96 | LTA4H (0.49) | LTA4HALDH1A1KDM4ECA1CA2 | |
| Hydrochloric Acid SCHEMBL6243653 | 0.92 | ALDH1A1 (0.47) | LTA4HALDH1A1KDM4ECA1CA2 | |
| SCHEMBL11238239 | 0.82 | LIPE (0.41) | LTA4HALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL2091737 | 0.80 | MEN1 (0.45) | LTA4HMEN1KMT2AHRH3MAOB | |
| SCHEMBL2091733 | 0.80 | LTA4H (0.37) | LTA4HCA1CA2CA9KIF11 | |
| SCHEMBL11184544 | 0.78 | LTA4H (0.48) | LTA4HALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL188044 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MEN1HPGDKMT2AHRH3 | |
| SCHEMBL31114511 | 0.74 | EPHX2 (0.50) | ALDH1A1KDM4ETSHRHRH3 | |
| SCHEMBL29995406 | 0.73 | ALDH1A1 (0.50) | LTA4HALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL4324629 | 0.72 | KMT2A (0.44) | LTA4HALDH1A1KDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010474-A1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-06-25 | — | — | WO | disclosed |