Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.49 |
| ▸ | VCP | P55072 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238483 | 0.89 | MAPT (0.48) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL11238478 | 0.89 | MAPT (0.48) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3100263 | 0.87 | CYP1A2 (0.66) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3100253 | 0.87 | CYP1A2 (0.66) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL34462897 | 0.80 | MAPT (0.55) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL1804005 | 0.77 | PRMT1 (0.54) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL30823746 | 0.77 | PRMT1 (0.54) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL34462751 | 0.77 | PRMT1 (0.57) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL1569821 | 0.77 | PRMT1 (0.54) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL1801907 | 0.77 | PRMT1 (0.54) | MAPTALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318986-A | Enzyme assays | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-03-09 | — | — | US | disclosed |
| EP-0007372-A1 | Methods and reagents for the assay of enzymes | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1980-02-06 | — | — | EP | disclosed |
| WO-1979000255-A1 | ENZYME ASSAYS | NAT RES DEV (GB) | 1979-05-17 | — | — | WO | disclosed |