Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | GALR2 | O43603 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804005 | 1.00 | PRMT1 (0.54) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL1569821 | 1.00 | PRMT1 (0.54) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL8639564 | 0.88 | VCP (0.56) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL8639566 | 0.88 | VCP (0.56) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL34462827 | 0.88 | VCP (0.56) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL22027897 | 0.84 | LMNA (0.59) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL22027898 | 0.84 | LMNA (0.59) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL3100253 | 0.83 | CYP1A2 (0.66) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL3100263 | 0.83 | CYP1A2 (0.66) | PRMT1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL20563457 | 0.81 | MAPT (0.49) | PRMT1MAPTALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655681-B | Heterocyclylamino-substituted triazoles as modulators of Rho-related protein kinases | 莱德克斯制药公共有限公司 | 2024-01-05 | — | — | CN | disclosed |