Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 10/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 10/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | FBP1 | P09467 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100263 | 1.00 | CYP1A2 (0.66) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL29652580 | 0.87 | TLR9 (0.63) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL8638229 | 0.87 | TLR9 (0.63) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL7418807 | 0.87 | TLR9 (0.63) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL31069475 | 0.87 | TLR9 (0.63) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL11238477 | 0.87 | MAPT (0.49) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL34463065 | 0.86 | FBP1 (0.50) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL34462897 | 0.86 | MAPT (0.55) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL11238478 | 0.84 | MAPT (0.48) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 | |
| SCHEMBL11238483 | 0.84 | MAPT (0.48) | CYP1A2CYP1A1CYP1B1NFE2L2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3081745-A | — | — | None | — | — | JP | disclosed |
| US-20150266850-A1 | SUBSTITUTED TOLYL FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-09-24 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2009006-A1 | UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2008-12-31 | — | — | EP | disclosed |
| JP-H0381745-A | ORGANIC NONLINEAR OPTICAL MATERIAL | SEKISUI CHEM CO LTD | 1991-04-08 | — | — | JP | disclosed |
| US-4663482-A | Intermediates for preparing 7-(2-aminoethyl)-1,3-benzthia- or oxa- zol-2(3H)-ones | SMITHKLINE BECKMAN CORPORATION (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0174811-A2 | 7-(2-aminoethyl)-1,3-Benzthia- or oxa- zol-2(3H) -ones | SMITHKLINE BECKMAN CORPORATION (US) | 1986-03-19 | — | — | EP | disclosed |
| US-4554284-A | 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones | SMITHKLINE BECKMAN CORPORATION (US) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266850-A1 | SUBSTITUTED TOLYL FUNGICIDES | TH, CYP1B1, CYP1A1 | CYP1A2 17/4885CYP1A1 3/4885CYP1B1 2/4885 |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | UROD, UTS2R, SLC14A1 | CYP1A2 3328/4885CYP1A1 4648/4885CYP1B1 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.