Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238537 | 1.00 | NFE2L2 (0.39) | NFE2L2CYP19A1HSD11B1KDM4EALDH1A1 | |
| SCHEMBL3450459 | 0.82 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2FBP1 | |
| SCHEMBL27776608 | 0.81 | CYP19A1 (0.39) | NFE2L2CYP19A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8927087 | 0.81 | CYP19A1 (0.41) | CYP19A1KDM4EALDH1A1KMT2A | |
| SCHEMBL8927085 | 0.81 | CYP19A1 (0.41) | CYP19A1KDM4EALDH1A1KMT2A | |
| SCHEMBL5319610 | 0.78 | CYP19A1 (0.46) | CYP19A1ALDH1A1FBP1 | |
| SCHEMBL9821376 | 0.70 | GAA (0.60) | CYP19A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9821379 | 0.70 | GAA (0.60) | CYP19A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11380733 | 0.68 | — | — | |
| SCHEMBL27584580 | 0.67 | CYP19A1 (0.50) | CYP19A1KDM4EALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| EP-0008651-B1 | DERIVATIVES OF TRIAZOLE, PROCESS FOR THEIR PRODUCTION AND INSECTICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0008651-A1 | Derivatives of triazole, process for their production and insecticides containing them | BASF Aktiengesellschaft (DE) | 1980-03-19 | — | — | EP | disclosed |