Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821379 | 1.00 | GAA (0.60) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL12450311 | 0.83 | GAA (0.60) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL9821551 | 0.78 | POLB (0.48) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL9821549 | 0.78 | POLB (0.48) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL12275405 | 0.71 | ALDH1A1 (0.64) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL12275406 | 0.71 | ALDH1A1 (0.64) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL9821384 | 0.70 | HPGD (0.43) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL9821500 | 0.70 | POLB (0.35) | GAAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL11238537 | 0.70 | NFE2L2 (0.39) | ALDH1A1KDM4ECYP19A1SMN1; SMN2 | |
| SCHEMBL11238533 | 0.70 | NFE2L2 (0.39) | ALDH1A1KDM4ECYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041458-A | Fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0349580-B1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0349580-A1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES. | DU PONT (US) | 1990-01-10 | — | — | EP | disclosed |
| WO-1988007040-A1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-22 | — | — | WO | disclosed |
| EP-0283245-A1 | Fungicidal aminotriazoles and aminoimidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-21 | — | — | EP | disclosed |