Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243548 | 0.94 | ALDH1A1 (0.53) | KDM4ELMNAALDH1A1QPCTGAA | |
| SCHEMBL11239177 | 0.89 | KDM4E (0.53) | KDM4ELMNAALDH1A1QPCTGAA | |
| SCHEMBL11249292 | 0.87 | MEN1 (0.53) | KDM4ELMNAALDH1A1QPCTGAA | |
| SCHEMBL11241810 | 0.84 | MEN1 (0.52) | KDM4ELMNAALDH1A1QPCTGAA | |
| SCHEMBL11241916 | 0.84 | QPCT (0.48) | KDM4EALDH1A1QPCTMEN1KMT2A | |
| SCHEMBL11251785 | 0.83 | KDM4E (0.49) | KDM4ELMNAALDH1A1QPCTGAA | |
| SCHEMBL11242901 | 0.83 | QPCT (0.46) | KDM4EALDH1A1QPCT | |
| SCHEMBL11233658 | 0.82 | CYP19A1 (0.45) | LMNAMEN1KMT2A | |
| SCHEMBL11241723 | 0.82 | ALDH1A1 (0.54) | KDM4ELMNAALDH1A1QPCTGAA | |
| SCHEMBL11245761 | 0.81 | LMNA (0.43) | KDM4ELMNAQPCTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |