Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238567 | 0.94 | KDM4E (0.52) | ALDH1A1KDM4ELMNAQPCTGAA | |
| SCHEMBL11241723 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMAPK1TBXAS1 | |
| SCHEMBL11233770 | 0.87 | MEN1 (0.49) | ALDH1A1KDM4ELMNAMAPK1TBXAS1 | |
| SCHEMBL11246654 | 0.83 | QPCT (0.44) | ALDH1A1KDM4EMAPK1QPCTMEN1 | |
| SCHEMBL11243314 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPK1TBXAS1 | |
| SCHEMBL11239177 | 0.82 | KDM4E (0.53) | ALDH1A1KDM4ELMNAQPCTGAA | |
| SCHEMBL11240587 | 0.82 | TP53 (0.44) | ALDH1A1KDM4EQPCTCYP19A1 | |
| SCHEMBL11253540 | 0.82 | TBXAS1 (0.45) | TBXAS1QPCTCYP19A1LTA4H | |
| SCHEMBL11249292 | 0.81 | MEN1 (0.53) | ALDH1A1KDM4ELMNAQPCTGAA | |
| SCHEMBL11236382 | 0.80 | KMT2A (0.47) | ALDH1A1KDM4ELMNAQPCTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |