Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995692 | 0.80 | ADRA2B (0.50) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL13995693 | 0.80 | ADRA2B (0.50) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL6729783 | 0.78 | AOC3 (0.53) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL13024949 | 0.77 | RIPK1 (0.45) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL11658797 | 0.77 | AOC3 (0.54) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL1834929 | 0.76 | TSHR (0.51) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL6054336 | 0.76 | TSHR (0.51) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL1834931 | 0.76 | TSHR (0.51) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL1593286 | 0.75 | TSHR (0.50) | LMNAAOC3KDM4EKMT2AMEN1 | |
| SCHEMBL10438182 | 0.75 | SIGMAR1 (0.46) | LMNAAOC3KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313896-A | ANTIDEPRESSANTS, PSYCHOTROPIC AGENTS | ELI LILLY AND COMPANY (US) | 1982-02-02 | — | — | US | disclosed |