Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315779 | 1.00 | HSD17B1 (0.67) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL11236609 | 0.92 | HSD17B1 (0.64) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL7124870 | 0.88 | HSD17B1 (0.64) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL7124873 | 0.88 | HSD17B1 (0.64) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL22692617 | 0.86 | HSD17B1 (0.60) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL15307738 | 0.86 | HSD17B1 (0.79) | HSD17B1LMNAMAPTESR1HSD17B10 | |
| SCHEMBL15979565 | 0.86 | HSD17B1 (0.71) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL11231177 | 0.86 | HSD17B1 (0.71) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL11865928 | 0.85 | ESR1 (0.74) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL9558249 | 0.85 | LMNA (0.69) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |
| US-4333928-A | PROGESTATIONAL ACTIVITY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |