Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124870 | 1.00 | HSD17B1 (0.64) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL12418539 | 0.89 | HSD17B1 (0.63) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL11315779 | 0.88 | HSD17B1 (0.67) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL11239229 | 0.88 | HSD17B1 (0.67) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL12379508 | 0.88 | HSD17B1 (0.80) | HSD17B1LMNAMAPTSMN1; SMN2ESR1 | |
| SCHEMBL7079631 | 0.88 | HSD17B1 (0.54) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL12379505 | 0.87 | USP2 (0.64) | HSD17B1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11236609 | 0.86 | HSD17B1 (0.64) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL7079771 | 0.85 | HSD17B1 (0.65) | HSD17B1LMNAMAPTESR1KDM4E | |
| SCHEMBL11865928 | 0.84 | ESR1 (0.74) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670347-B2 | Selective estrogens that show preference for one of the two known estogen receptors | SCHERING AG (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20020156271-A1 | 19-nor-17alpha-pregna-1,3,5 (10) -trien-17beta-ols with a 21, 16alpha-lactone ring | JENAPHARM GMBH & CO. KG (DE) | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156271-A1 | 19-nor-17alpha-pregna-1,3,5 (10) -trien-17beta-ols with a 21, 16alpha-lactone ring | HSD17B11, CYP17A1, CYP19A1 | HSD17B1 10/4885LMNA 2804/4885MAPT 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.