Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Ethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL11239448 | 1.00 | DNM1 (0.35) | DNM1 | |
| Ethylamine SCHEMBL23910301 | 0.94 | — | — | |
| Ethylamine SCHEMBL473818 | 0.88 | — | — | |
| Ethylamine SCHEMBL9536323 | 0.88 | — | — | |
| Ethylamine SCHEMBL28837477 | 0.88 | — | — | |
| Ethylamine SCHEMBL9536330 | 0.88 | DNM1 (0.40) | DNM1 | |
| Ethylamine SCHEMBL9393989 | 0.88 | — | — | |
| Ethylamine SCHEMBL9393995 | 0.88 | — | — | |
| Ethylamine SCHEMBL127386 | 0.88 | DNM1 (0.40) | DNM1 | |
| Ethylamine SCHEMBL1331914 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328166-A | Production of substituted phenylurea | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4263219-A | METHYLATION IN TWO-PHASE REACTION MEDIUM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-04-21 | — | — | US | disclosed |