Eugenol

Eugenol

SCHEMBL11239686

C=CCc1ccc(O)c(OC)c1.COc1ccccc1O

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.85
ALOX5 P09917 4/20 0.85
CYP3A4 P08684 2/20 0.85
PTGS1 P23219 2/20 0.85
TRPM8 Q7Z2W7 2/20 0.85
AR P10275 1/20 0.85
GABRA1 P14867 4/20 0.62
GABRB2 P47870 4/20 0.62
PPARG P37231 2/20 0.61
PPARD Q03181 2/20 0.61
PPARA Q07869 1/20 0.61
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
TSHR P16473 2/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
TP53 P04637 1/20 0.55
CNR2 P34972 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyleugenol SCHEMBL26688181 0.93 ALDH1A1 (0.73) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL28883151 0.92 ALDH1A1 (0.93) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL788240 0.92 ALDH1A1 (1.00) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL20361 0.92 ALDH1A1 (1.00) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL29126189 0.92 ALDH1A1 (1.00) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL29364978 0.92 ALDH1A1 (1.00) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL662388 0.91 TRPM8 (0.90) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL27521002 0.91 TRPM8 (0.90) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL25377864 0.91 ALDH1A1 (0.97) ALDH1A1ALOX5CYP3A4PTGS1TRPM8
Eugenol SCHEMBL5030243 0.91 ALDH1A1 (0.97) ALDH1A1ALOX5CYP3A4PTGS1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4355136-A Solvent-resistant unsaturated polyester compositions EASTMAN KODAK COMPANY (US) 1982-10-19 US disclosed
US-4299927-A UNSATURATED POLYESTER AND A MODIFIED POLYOLEFIN EASTMAN KODAK COMPANY (US) 1981-11-10 US disclosed
US-4258143-A REACTION PRODUCT OF AN UNSATURATED POLYESTER AND A MODIFIED POLYOLEFIN EASTMAN KODAK COMPANY (US) 1981-03-24 US disclosed