Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246053 | 0.91 | IDO1 (0.40) | ALDH1A1IDO1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11243302 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2IDO1QPCT | |
| SCHEMBL11249904 | 0.88 | MEN1 (0.45) | ALDH1A1KDM4EQPCTCYP19A1CYP11B1 | |
| SCHEMBL11247563 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2IDO1QPCT | |
| SCHEMBL11239088 | 0.87 | CYP11B1 (0.49) | ALDH1A1KDM4ESMN1; SMN2IDO1NPSR1 | |
| SCHEMBL11251627 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2IDO1QPCT | |
| SCHEMBL11235305 | 0.86 | CYP19A1 (0.42) | QPCTCYP19A1CYP11B1CYP11B2MAPT | |
| SCHEMBL11241135 | 0.85 | HMOX1 (0.47) | — | |
| SCHEMBL11232771 | 0.83 | IDO1 (0.41) | ALDH1A1KDM4ESMN1; SMN2IDO1CYP19A1 | |
| SCHEMBL11228678 | 0.81 | MEN1 (0.46) | ALDH1A1KDM4EQPCTCYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |