Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251627 | 0.96 | ALDH1A1 (0.42) | ALDH1A1IDO1QPCTCYP19A1KDM4E | |
| SCHEMBL11243302 | 0.91 | ALDH1A1 (0.41) | ALDH1A1IDO1QPCTCYP19A1KDM4E | |
| SCHEMBL11250541 | 0.89 | HMOX1 (0.48) | IDO1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11239765 | 0.88 | ALDH1A1 (0.42) | ALDH1A1IDO1QPCTCYP19A1KDM4E | |
| SCHEMBL11246746 | 0.86 | MEN1 (0.50) | CYP19A1MAPTCYP11B1HMOX1 | |
| SCHEMBL11242952 | 0.86 | HMOX1 (0.49) | ALDH1A1IDO1QPCTKDM4ESMN1; SMN2 | |
| SCHEMBL11242726 | 0.85 | CYP11B1 (0.55) | IDO1CYP19A1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL11239983 | 0.85 | HMOX1 (0.44) | IDO1CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11243504 | 0.83 | HMOX1 (0.60) | HMOX1 | |
| SCHEMBL11249736 | 0.82 | HMOX1 (0.49) | QPCTCYP19A1MAPTCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |