Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619845 | 0.87 | NR4A1 (0.47) | NR4A1NR4A2NR4A3TAS2R14FABP4 | |
| SCHEMBL11239828 | 0.83 | LMNA (0.46) | TAS2R14FABP4LMNAGAAMEN1 | |
| SCHEMBL24895103 | 0.81 | HPGD (0.46) | NR4A1NR4A2NR4A3TAS2R14FABP4 | |
| SCHEMBL11245617 | 0.81 | TAS2R14 (0.42) | NR4A1NR4A2NR4A3TAS2R14FABP4 | |
| SCHEMBL29406795 | 0.79 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL27985 | 0.79 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL221518 | 0.78 | LMNA (0.62) | TAS2R14FABP4LMNAGAAALDH1A1 | |
| SCHEMBL30449216 | 0.78 | LMNA (0.62) | TAS2R14FABP4LMNAGAAALDH1A1 | |
| SCHEMBL10391427 | 0.77 | LMNA (0.45) | NR4A2TAS2R14LMNAGAAALDH1A1 | |
| SCHEMBL4104026 | 0.77 | CTNNB1 (0.43) | TAS2R14LMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331613-A | Process for the preparation of trifluoromethylnaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |