Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 3/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243140 | 0.83 | NPC1 (0.48) | FPR2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10906940 | 0.83 | NPC1 (0.44) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL8659039 | 0.81 | NPC1 (0.47) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL11238380 | 0.81 | TDP1 (0.55) | ITGA4ITGB1FPR2NPC1RAB9A | |
| SCHEMBL11388137 | 0.81 | ATM (0.42) | ITGA4ITGB1NPC1RAB9AATM | |
| SCHEMBL11390176 | 0.79 | ATM (0.45) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL10906894 | 0.79 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL9834629 | 0.79 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2MEN1RECQL | |
| SCHEMBL11235882 | 0.79 | ATM (0.46) | NPC1RAB9AATMSMN1; SMN2MAPT | |
| SCHEMBL10908649 | 0.78 | NPC1 (0.45) | NPC1RAB9AATMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |