Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906940 | 0.96 | NPC1 (0.44) | ATMRAB9ANPC1PKMMAPT | |
| SCHEMBL10910904 | 0.91 | NPC1 (0.42) | RAB9ANPC1PKMMAPTKMT2A | |
| SCHEMBL10906894 | 0.87 | NPC1 (0.43) | RAB9ANPC1 | |
| SCHEMBL11390176 | 0.85 | ATM (0.45) | ATMRAB9ANPC1PKMMAPT | |
| SCHEMBL11243575 | 0.84 | FAAH (0.42) | — | |
| SCHEMBL10909648 | 0.83 | MAPT (0.48) | RAB9ANPC1MAPTKMT2AKDM4E | |
| SCHEMBL8659039 | 0.81 | NPC1 (0.47) | ATMRAB9ANPC1PKMMAPT | |
| SCHEMBL11240030 | 0.81 | ITGA4 (0.44) | ATMRAB9ANPC1PKMMAPT | |
| SCHEMBL11235882 | 0.81 | ATM (0.46) | ATMRAB9ANPC1PKMMAPT | |
| SCHEMBL10909100 | 0.80 | SLC7A5 (0.44) | RAB9ANPC1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
| EP-0031974-A2 | New urea compounds and thiourea compounds, method of preparing the new compounds, and insecticidal compositions on the basis of these compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-07-15 | — | — | EP | disclosed |