Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243618 | 0.80 | LMNA (0.32) | MAOAMAOBSMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL30929883 | 0.65 | CYP4F2 (0.34) | L3MBTL1MAPT | |
| SCHEMBL638679 | 0.65 | MAOA (0.35) | MAOAMAOBPKMMAPK14GRM5 | |
| SCHEMBL543350 | 0.65 | MAOA (0.37) | MAOAMAOBPKMSMN1; SMN2RAB9A | |
| SCHEMBL6281711 | 0.64 | CNR2 (0.35) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL544376 | 0.62 | APOBEC3G (0.36) | MAOAMAOBPKMRAB9AL3MBTL1 | |
| SCHEMBL23181355 | 0.59 | MAOB (0.56) | MAOAMAOBSMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL27511263 | 0.57 | MAOA (0.45) | MAOAMAOBPKMRAB9AGAA | |
| SCHEMBL23070558 | 0.57 | HTT (0.40) | MAOBPKMSMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL19684473 | 0.55 | MAOB (0.40) | MAOAMAOBSMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358454-A | ANTIULCER AGENT | SCHERING CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |