Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CASR | P41180 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244044 | 0.89 | MAPT (0.69) | ADRB3ADRB1ADRB2MAPTKMT2A | |
| SCHEMBL20552597 | 0.88 | MAPT (0.77) | ADRB3ADRB1ADRB2MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11230526 | 0.88 | MAPT (0.68) | ADRB3ADRB1ADRB2MAPTKMT2A | |
| SCHEMBL11233869 | 0.86 | ADRB1 (0.64) | ADRB3ADRB1ADRB2MAPTKMT2A | |
| SCHEMBL11237765 | 0.86 | ADRB1 (0.64) | ADRB3ADRB1ADRB2MAPTKMT2A | |
| SCHEMBL2024020 | 0.82 | ADRB2 (0.70) | ADRB3ADRB1ADRB2 | |
| SCHEMBL2024026 | 0.82 | ADRB2 (0.70) | ADRB3ADRB1ADRB2 | |
| SCHEMBL2024023 | 0.82 | ADRB2 (0.70) | ADRB3ADRB1ADRB2 | |
| SCHEMBL11609943 | 0.81 | ADRB1 (0.76) | ADRB3ADRB1ADRB2MAPTKMT2A | |
| SCHEMBL11230720 | 0.81 | ADRB1 (0.67) | ADRB3ADRB1ADRB2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |