Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447131 | 0.96 | CA12 (0.42) | CA12CA6CA7CA9CA14 | |
| SCHEMBL29402314 | 0.85 | HRH4 (0.33) | ANPEP | |
| SCHEMBL28590650 | 0.82 | CA12 (0.40) | CA12CA6CA7CA9CA14 | |
| SCHEMBL32669028 | 0.80 | CA12 (0.42) | CA12CA6CA7CA9CA14 | |
| SCHEMBL9820488 | 0.80 | CA12 (0.33) | CA12CA6CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL27083609 | 0.77 | ALDH1A1 (0.41) | LMNAALDH1A1ANPEP | |
| SCHEMBL28730897 | 0.76 | KDM4E (0.37) | TP53KDM4E | |
| SCHEMBL2050372 | 0.72 | CA12 (0.33) | CA12CA6CA7CA9CA14 | |
| SCHEMBL7146673 | 0.71 | HTR2A (0.32) | LMNAALDH1A1TP53KDM4ECYP2C19 | |
| SCHEMBL14980523 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317123-A | Thermal recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1982-02-23 | — | — | US | claimed |
| US-8029577-B2 | Lightening and/or dyeing of human keratin fibres via a composition comprising a particular amino silicon compound and composition and device | L'OREAL S.A. (FR) | 2011-10-04 | — | — | US | disclosed |
| US-7909889-B2 | Lightening and/or coloring human keratin fibers using at least one aminotrialkoxy silane or at least one aminotrialkenyloxy silane composition | L'OREAL S.A. (FR) | 2011-03-22 | — | — | US | disclosed |
| US-7905927-B2 | Method for lightening and/or coloring human keratin fibers using a composition comprising an aminotrialkoxy silane or aminotrialkenyloxy silane compound and device | L'OREAL, SA (FR) | 2011-03-15 | — | — | US | disclosed |
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | disclosed |
| US-20100297049-A1 | LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND AND COMPOSITION AND DEVICE | L'OREAL S.A. (FR) | 2010-11-25 | — | — | US | disclosed |
| US-20100275387-A1 | LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | KRT18, FABP4, APMAP | CA12 1685/4885CA6 2784/4885CA7 2074/4885 |
| US-20100275387-A1 | LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION | KRT18, FABP4, ALDH7A1 | CA12 723/4885CA6 1264/4885CA7 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.