Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239155 | 0.88 | HSD17B10 (0.46) | RYR2HSD17B10TDP1MEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL11235761 | 0.81 | RYR2 (0.36) | RYR2HSD17B10SLC6A4KDM4EALDH1A1 | |
| SCHEMBL27765463 | 0.76 | PTGS2 (0.39) | RYR2HSD17B10SLC6A4KDM4EALDH1A1 | |
| SCHEMBL25668368 | 0.75 | KDM4E (0.47) | HSD17B10TDP1KMT2ASLC6A4KDM4E | |
| SCHEMBL27064478 | 0.73 | SLC6A4 (0.33) | RYR2SLC6A4VHLELOCELOB | |
| SCHEMBL25668370 | 0.72 | VHL (0.31) | SLC6A4VHLELOCELOB | |
| SCHEMBL25668374 | 0.72 | SLC6A4 (0.31) | HSD17B10TDP1KMT2ASLC6A4KDM4E | |
| SCHEMBL25668369 | 0.72 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL25668371 | 0.72 | SLC6A4 (0.32) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL11341479 | 0.71 | PTGS2 (0.33) | RYR2HSD17B10SLC6A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341792-A | ANTIDIABETIC AND CARDIOTONIC AGENTS | PFIZER INC. (US) | 1982-07-27 | — | — | US | disclosed |