Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203583 | 0.80 | KDM4E (0.33) | KMT2AGAA | |
| SCHEMBL11242674 | 0.73 | LMNA (0.40) | BRD4BRD2LMNATSHRCA12 | |
| SCHEMBL6047009 | 0.72 | — | — | |
| SCHEMBL9587421 | 0.70 | LMNA (0.38) | BRD4BRD2LMNATSHRCA12 | |
| SCHEMBL11245719 | 0.69 | LMNA (0.37) | BRD4BRD2LMNATSHRCA12 | |
| SCHEMBL9628933 | 0.68 | TSHR (0.45) | BRD4BRD2LMNATSHRCA12 | |
| SCHEMBL11514638 | 0.67 | LMNA (0.43) | BRD4BRD2LMNATSHRCA12 | |
| SCHEMBL22635867 | 0.66 | BRD4 (0.41) | BRD4BRD2LMNATSHRALDH1A1 | |
| SCHEMBL11512589 | 0.66 | KMT2A (0.39) | BRD4BRD2LMNATSHRCA12 | |
| SCHEMBL11243325 | 0.66 | GAA (0.38) | BRD4BRD2LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324787-A | 2-Oxo-1-pyrrolidineacetic acid compounds and their medicinal use | TROPONWERKE GMBH & CO., KG (DE) | 1982-04-13 | — | — | US | disclosed |