Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240680 | 0.74 | NPSR1 (0.36) | GAAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8892997 | 0.70 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11251996 | 0.70 | ALDH1A1 (0.39) | GAAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12473809 | 0.68 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11242674 | 0.67 | LMNA (0.40) | GAAALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11240360 | 0.66 | BRD4 (0.36) | GAAALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL28929645 | 0.65 | ALDH1A1 (0.49) | GAAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9587421 | 0.65 | LMNA (0.38) | ALDH1A1KMT2APOLBLMNAPKM | |
| SCHEMBL11513983 | 0.64 | TRPM8 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C9MEN1 | |
| SCHEMBL11245719 | 0.64 | LMNA (0.37) | ALDH1A1CYP1A2KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324787-A | 2-Oxo-1-pyrrolidineacetic acid compounds and their medicinal use | TROPONWERKE GMBH & CO., KG (DE) | 1982-04-13 | — | — | US | disclosed |