SCHEMBL9203583

SCHEMBL9203583

CC(=O)N([C@H]1CCCNC(=O)C1)N1CCCC1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240360 0.80 BRD4 (0.36) GAAKMT2A
SCHEMBL3108291 0.64 MGLL (0.40) KDM4EPOLBL3MBTL1KMT2A
SCHEMBL1198241 0.64 KMT2A (0.41) KDM4EGAAPOLBL3MBTL1KMT2A
SCHEMBL11242674 0.62 LMNA (0.40) KDM4EGAAPOLBKMT2A
SCHEMBL4618063 0.61 MGLL (0.31) L3MBTL1
SCHEMBL8312942 0.60 ALDH1A1 (0.42) KDM4EL3MBTL1
SCHEMBL9162699 0.60 ALDH1A1 (0.42) KDM4EL3MBTL1
SCHEMBL9587421 0.60 LMNA (0.38) POLBKMT2A
2-Pyrrolidone SCHEMBL887016 0.60 OR51E2 (0.62) KDM4EGAAPOLBL3MBTL1KMT2A
SCHEMBL3122699 0.59 OR51E2 (0.40) KDM4EGAAPOLBL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0462949-B1 1-alkyl-3-(acylamino)-epsilon-caprolactames as enhancers of learning and memory and pharmaceutical compositions containing same SIGMA TAU IND FARMACEUTI (IT) 1995-12-06 EP disclosed
US-5155102-A Cognition activators, analgesics SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1992-10-13 US disclosed
EP-0462949-A1 1-alkyl-3-(acylamino)-epsilon-caprolactames as enhancers of learning and memory and pharmaceutical compositions containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1991-12-27 EP disclosed