SCHEMBL11240411

SCHEMBL11240411

O=C(O)OC1OCCCO1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6444644 0.90
SCHEMBL28153885 0.78 TSHR (0.35)
SCHEMBL11286216 0.78 ATM (0.32)
SCHEMBL9615160 0.73 TSHR (0.30) ALDH1A1
SCHEMBL21996328 0.73 CHRM2 (0.38) ALDH1A1
SCHEMBL11632239 0.72 BCHE (0.46)
SCHEMBL20578240 0.72 ALDH1A1 (0.43) ALDH1A1
SCHEMBL3886205 0.71
SCHEMBL486112 0.71
SCHEMBL3874885 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046488-A3 SUBSTITUTED 2,5,7-TRIOXA-BICYCLO(2.2.2)OCTAN-6-ONES, 3,6,8-TRIOXA-BICYCLO(3.2.1)OCTAN-4-ONES AND 1,3-DIOXANE-CARBOXYLIC ACID AND 1,3-DIOXOLANE-2-CARBOXYLIC ACID COMPOUNDS, AND THEIR PREPARATION HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1982-06-02 EP disclosed
EP-0046488-A2 Substituted 2,5,7-trioxa-bicyclo(2.2.2)octan-6-ones, 3,6,8-trioxa-bicyclo(3.2.1)octan-4-ones and 1,3-dioxane-carboxylic acid and 1,3-dioxolane-2-carboxylic acid compounds, and their preparation HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1982-03-03 EP disclosed