Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209219 | 0.91 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL28303143 | 0.76 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL2125922 | 0.76 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL28153885 | 0.76 | TSHR (0.35) | CHRM2CHRM4CHRM1CHRM3POLB | |
| SCHEMBL27701465 | 0.75 | ALDH1A1 (0.44) | BCHEALDH1A1NAAA | |
| SCHEMBL3812571 | 0.75 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL20357987 | 0.75 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL11240411 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27564583 | 0.72 | — | — | |
| SCHEMBL6929108 | 0.72 | NAAA (0.47) | BCHENAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887353-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | Comet Therapeutics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020113209-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | COMET THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |