Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | DRD2 | P14416 | 1/20 | 0.71 |
| ▸ | PTGES | O14684 | 8/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407060 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| SCHEMBL11160288 | 0.86 | KDM4E (0.82) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| SCHEMBL11158740 | 0.83 | KDM4E (0.82) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| Lonazolac SCHEMBL25221 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| SCHEMBL11159845 | 0.83 | KDM4E (0.82) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| SCHEMBL11251957 | 0.82 | KDM4E (0.76) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| Lonazolac SCHEMBL1478078 | 0.82 | KDM4E (0.97) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| Lonazolac SCHEMBL287156 | 0.82 | KDM4E (0.97) | KDM4EALDH1A1DRD2PTGESALOX5 | |
| SCHEMBL23928648 | 0.81 | L3MBTL1 (0.68) | KDM4EALDH1A1MAPTUSP2HPGD | |
| SCHEMBL11540126 | 0.80 | MAPT (0.53) | KDM4EALDH1A1DRD2PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |