Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 14/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TPH1 | P17752 | 1/20 | 0.37 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850073 | 0.77 | MTOR (0.40) | MTORJAK2JAK1JAK3PIK3CA | |
| SCHEMBL11479633 | 0.75 | MAT2A (0.41) | MTORMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11851618 | 0.75 | TSHR (0.44) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11846857 | 0.75 | TSHR (0.44) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL11848829 | 0.71 | ABCC1 (0.40) | ABCC1POLBALDH1A1 | |
| SCHEMBL11847580 | 0.70 | PDE5A (0.38) | ABCC1POLBALDH1A1 | |
| SCHEMBL11851637 | 0.70 | HCAR1 (0.41) | JAK2JAK1JAK3MEN1KMT2A | |
| SCHEMBL11016276 | 0.69 | PDE5A (0.54) | MTORMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11849926 | 0.69 | MAPK1 (0.41) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10977785 | 0.67 | ADORA2A (0.52) | MTORPIK3CAGSK3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061913-A2 | Herbicidal heterooxybenzenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-10-06 | — | — | EP | disclosed |
| EP-0048143-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0045196-A2 | Herbicidal benzothiophene and benzofuran sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-03 | — | — | EP | disclosed |
| US-3983116-A | Herbicidal triazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-09-28 | — | — | US | disclosed |