SCHEMBL11240731

SCHEMBL11240731

BrC(Br)(Br)Cc1cccnc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.59
CYP1A2 P05177 3/20 0.56
CYP3A4 P08684 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 1/20 0.56
HIF1A Q16665 1/20 0.56
BTN3A1 O00481 1/20 0.55
PDE3A Q14432 1/20 0.55
CYP2D6 P10635 1/20 0.54
CYP2A6 P11509 1/20 0.53
CHRNA7 P36544 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HRH1 P35367 2/20 0.50
CHRNB2 P17787 2/20 0.50
CHRNA4 P43681 2/20 0.50
CHRM2 P08172 1/20 0.48
NAPRT Q6XQN6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31358573 0.80 CYP1A2 (0.55) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL11231844 0.80 FDPS (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL74145 0.80 CYP1A2 (0.55) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL95744 0.80 FDPS (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL29582746 0.80 FDPS (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
Ammonia Solution, Strong SCHEMBL27962089 0.78 CHRNB2 (0.57) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL7382527 0.77 FDPS (0.54) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL15516269 0.77 CYP1A2 (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL14036231 0.77 CYP1A2 (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL19117642 0.77 CYP1A2 (0.51) FDPSCYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4339455-A 1-(3-Pyridyl)-2,2,2-trihaloethyl compounds and fungicidal compositions containing the same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1982-07-13 US disclosed
US-4189486-A FUNGICIDES CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1980-02-19 US disclosed